What’s the Harm in Taking an Antidepressant?

Source: KellyBroganMD.com
Dr. Kelly Brogan M.D.
November 8, 2016

what's-the-harm

We know that all drugs have side effects. That’s just part of the deal right? But is it really possible that an antidepressant can cause a sane person to act like a cold-blooded criminal?

I imagined my audience would be wondering as much as I arrived to an unseasonably chilly day at King’s College in London. I was there to share what I have learned about the medications that I so dutifully and faithfully prescribed during the early part of my career, and also about the deep potential for healing depression in simple, safe ways, according to the latest science.

The day before my flight, I had received an email from a man who I would choose to invite on stage with me that day. His name is David Carmichael and he wrote:

“I took the life of my 11-year-old son Ian on July 31, 2004 in a Paxil-induced state of psychosis and was charged with first degree murder. I was judged to be “not criminally responsible on account of a mental disorder” in September 2005 and received an absolute discharge from the forensic psychiatric system (in Ontario, Canada) in December 2009. I’ve been off all prescription drugs since September 2010. Prior to our family tragedy, I was a physical active sports consultant with no history of violence or mental illness.”

He told an audience of clinicians and patients, that day, about how it is that a normal citizen, prescribed a seemingly safe medication for work-related stress, goes on to commit a heinous act of violence against his beloved child. This academic classroom was heaving with grief when he finished his description of events.

This must be rare, right? Totally anomalous?

Wrong.

It has become my contention that the Russian Roulette that is played with each new prescription of psychotropic medication violates the physician’s most primal tenet – first do no harm – and does so in the absence of anything approximating informed consent.

Violence as a Side Effect?

Thankfully, we are often given multiple chances to wake up to a greater truth. It’s becoming easier than ever. With grassroots platforms like madinamerica.com, the information is out there, when you are ready to look beyond main stream media to what the real victims are claiming.

The truth about antidepressants and violence is also in the most recently published literature, including a critical review, hot off the press, by Carvalho et al where the authors dive into the research on the supposed safety of SSRIs and SNRIs. In this document, they present an evidence-based horror menagerie of ways in which a simple antidepressant can derail your life if it doesn’t take it. Leaving patients with new medical diagnoses, antidepressants prescribed often for difficult transitions in life like divorces and deaths, carry documented risks that your doctor cannot possibly tell you about because if they knew of them, they would put down their prescription pad immediately.

Let’s take a tour. Neatly summarized here, the adverse effects of antidepressants can sound like that droning voice in TV ads that we are inured to because we have been told these “side effects are rare, and outweighed by the benefits.”

But the benefits are shockingly limited so, let’s take a closer look at those side effects…

harm image

The Risks That Made Me Quit Prescribing

Having always represented antidepressants as safe and effective to my patients, I put down my prescription pad after learning 3 facts about psychiatric medications:

  • They result in worse long-term outcomes [1]
  • They are debilitatingly habit forming [2] [3] [4]
  • They cause unpredictable violence [5] [6]

These insights were apparently just the tip of the iceberg. Several years into the horror stories of patient experiences and new relationships with grassroots activists, I am left wondering. What on earth are these meds? How could biochemistry have ever manifested molecules capable of derailing, distorting, and suppressing the human experience to this extent?

With more unknowns than knowns at this point, the signal of harm is growing and patient alignment with this model of care, diminishing.

I pulled some choice phrases from the paper for your further enlightenment below but suffice it to say that many of these side effects are major gamechanging problems if not life-ending tragedies that render the placebo-level performance of these medications totally unacceptable.

Gut disturbance: “Some of the most frequently reported side effects associated with the use of SSRIs and serotonin noradrenaline reuptake inhibitors (SNRIs) include nausea, diarrhea, dyspepsia, GI bleeding and abdominal pain.”

Liver toxicity: “Two main mechanisms may be involved in antidepressant- induced liver toxicity, namely a metabolic component and/or an immuno-allergic pathway. A hypersensitivity syndrome with fever and rash as clinical manifestations, as well as with autoantibodies and eosinophilia, and a short latency period (1–6 weeks) point to a predominantly immunoallergic pathophysiological mechanism, whereas a lack of hypersensitivity syndrome and a longer latency period (i.e. 1 month to 1 year) points to an idiosyncratic metabolic mechanism.”

Weight gain: “Notwithstanding the complexity of the clinical scenario, compelling evidence indicates that the use of most antidepressants may increase weight in a significant proportion of patients.”

Heart problems: “SSRIs and SNRIs may promote a decrement in heart rate variability (HRV). Although the impact of the effects of antidepressants on HRV remains to be established, data indicate that a lower HRV is a significant predictor of incident cardiovascular events.”

Urinary problems: “SSRIs can cause urinary retention by acting on central micturition pathways. Serotonin may increase the central sympathetic outflow leading to urinary storage, and at the same time inhibits parasympathetic flow, which affects voiding.”

Sexual dysfunction: “…a significant body of data shows that antidepressants may differentially affect sexual function in multiple aspects, leading to reductions in libido, arousal dysfunction (erection in males and vaginal lubrication in females) and orgasmic dysfunctions.”

Salt imbalance: “The mechanisms of SSRI-induced hyponatremia remain incompletely elucidated, but these agents can act by either increasing the release of antidiuretic hormone (ADH) or increasing the sensitivity to ADH resulting in a clinical picture similar to the syndrome of inappropriate secretion of ADH.”

Osteoporosis/Bone weakening: “The use of SSRIs has been associated with a reduction in bone mineral density (BMD) and a consistent higher risk of fractures.”

Bleeding: “All serotonergic antidepressants have been associated with an increased risk of bleeding. The most likely mechanism responsible for these adverse reactions is a reduction of serotonin reuptake by platelets, although other mechanisms have also been implicated.”

Nervous system dysfunction: “All kinds of EPS [extrapyramidal symptoms] are seen in patients taking antidepressants, but akathisia appears to be the most common presentation followed by dystonic reactions, parkinsonian movements and tardive dyskinesia…Headache was one of the most common side effects associated with the use of antidepressants in a large retrospective cohort of adolescents and adults.”

Sweating: “Most studies indicate that approximately 10% of patients on SSRIs may develop excessive sweating, although the incidence may be higher for paroxetine.”

Sleep disturbances: “The SSRIs and venlafaxine are associated with increased REM sleep latency and a reduction in the overall time spent in the REM phase while sleeping.”

Mood changes: “Many patients taking SSRIs have reported experiencing emotional blunting. They often describe their emotions as being ‘damped down’ or ‘toned down’, while some patients refer to a feeling of being in ‘limbo’ and just ‘not caring’ about issues that were significant to them before…Furthermore, an activation syndrome in which patients taking antidepressants may experience anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness and impulsivity in the first 3 months of treatment may ensue.”

Suicidality: “The incidence of suicide and attempted suicide has been a frequently underreported adverse outcome across antidepressant RCTs.”

Overdose toxicity: “Patients with MDD are at increased risk of suicide and overdosing of prescribed medications is a common method used to attempted suicide.”

Withdrawal Syndrome: “These symptoms include flu-like symptoms, tremors, tachycardia, shock-like sensations, paresthesia, myalgia, tinnitus, neuralgia, ataxia, vertigo, sexual dysfunction, sleep disturbances, vivid dreams, nausea vomiting, diarrhea, worsening anxiety and mood Instability.”

Eye disease: “A subset of patients taking SSRIs reports nonspecific visual disturbances…SSRIs may increase intraocular pressure and lead to the emergence of angle-closure glaucoma…A nested case-control study found a higher likelihood of cataracts after exposure to newer generation antidepressants.”

Hormonal imbalance: “Long-standing increases in peripheral prolactin levels are occasionally observed in patients using ADs, including SSRIs [208] ; hyperprolactinemia may have deleterious health consequences (e.g. a decrease in BMD [bone mineral density] and hypogonadism).”

Pregnancy/Breastfeeding risk: “Most of the data describing the presence of birth defects associated with SSRI use have been based on observational studies and drug registries. Therefore, the clinical significance of these data is questionable.”

Cancer risk: “Preclinical studies have found that antidepressants can increase the growth of fibrosarcomas and melanomas, and may also promote mammary carcinogenesis.”

Whew! Now that’s depressing. And why don’t you know about these? Because your doctor doesn’t. I recently learned of a patient who was prescribed an antidepressant simultaneous to an antibiotic “just in case the antibiotic caused depression or mood changes”. We are trained to treat these medications as a “why not” application of pharmacology, and the truth is that, as the authors state:

the history of toxicology reminds us vividly of the lag that often occurs between the first approval of a drug for use in humans and the recognition of certain adverse events from that drug.”

Taking these risks seems all the more unecessary with the robust outcomes of lifestyle medicine – multimodal, multi-tier interventions that are low cost, immediately available, and side effect free. As the authors conclude:

The findings of this review suggest that long-term treatment with new generation ADs should be avoided if alternative treatments are available.”

I would have to agree and affirm that these “alternative” treatments are indeed available. These treatments offer not only resolution of symptoms and elimination/avoidance of meds, but an entirely new experience of self. This is not about getting “back to normal,” it’s about integration, evolution, and vitality. I’ve been working for several years to make self-healing toolkits available to everyone considering an antidepressant or looking to come off of one for less than the price of one doctor visit. Check it out!

[1] http://www.power2u.org/downloads/AnatomyofanEpidemic-SummaryofFindings-Whitaker.pdf
[2] https://www.karger.com/Article/FullText/371865
[3] http://www.madinamerica.com/psychiatric-drug-withdrawal/#/home/
[4] http://kellybroganmd.com/stop-madness-coming-psych-meds/
[5] http://kellybroganmd.com/homicide-and-the-ssri-alibi/

Read More At: KellyBroganMD.com

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© Kelly Brogan MD. This work is reproduced and distributed with the permission of Kelly Brogan MD. For more articles, sign up for the newsletter at kellybroganmd.com.

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Kelly Brogan, MD

Kelly Brogan, M.D. is a Manhattan-based holistic women’s health psychiatrist, author of the New York Times bestselling book, A Mind of Your Own, and co-editor of the landmark textbook, Integrative Therapies for Depression. She completed her psychiatric training and fellowship at NYU Medical Center after graduating from Cornell University Medical College, and has a B.S. from MIT in Systems Neuroscience. View full bio. Want to share this article on your own blog? View our reposting guidelines.

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Why should it take 14 years to learn a drug’s safety risks?

Depression More Common In People Who Talk About Themselves
Source: PostBulletin.com
John Scott
September 21, 2016

How would you describe the behavior of a teenager who takes 80 tablets of of an over-the-counter medication that’s deadly in high doses? Or an adolescent who had a disagreement with her mother, then overdoses on prescription pills? Or a child that had to be admitted to the hospital for severe suicidal and homicidal thinking?

Most people would call that becoming suicidal.

The makers of Paxil, in an influential 2001 research paper signed by some of the leading figures in child and adolescent psychiatry — including the current president of the American Academy of Child and Adolescent Psychiatry — called it “emotional lability.”

Why would you give such a confusing name to such apparently suicidal actions? To hide them, of course.

That’s the best explanation that comes to mind after the findings published in the journal BMJ last week — 14 years later — that the blockbuster antidepressant is neither safe nor effective in the treatment of depression in adolescents and children. In fact, the study found, it is far more dangerous than previously realized — the drug caused 11 out of 93 children to develop suicidal behaviors, compared to just 1 out of 87 on a placebo. The original paper only reported five such events on Paxil.

The recent news about the distortion of the clinical trial that put millions of kids on Paxil in the U.S. did not arise thanks to the makers of the pill, or the FDA, or the health media. As former Boston Globe reporter Allison Bass described in her 2008 book “Side Effects,” the data that paved the way for last week’s study came into public domain thanks to a series of accidents.

Paxil’s undisclosed liabilities came to light because a TV reporter in Scotland thought the term “emotional lability” made no sense, did a show about it, then an insider at the drug company leaked some emails showing the company knew the drug wasn’t safe or effective, which led then-New York attorney general Elliot Spitzer to sue the makers of the drug for fraud.

Almost no one was interested in that lawsuit — the makers of Paxil paid a fine and the world moved on. Except, thanks to Spitzer’s office, they had made public much of the data behind the trial, opaque decision-making that would have otherwise been called proprietary.

That means it’s not even clear that there is anything especially unique about Paxil. Other drugs, and especially drugs of this class, could have similar problems and yet we will never know because we do not get to see the soft underbelly of a clinical trial of a new drug — the many ways a manufacturer can use sleight-of-hand and ghostwriters to distort their findings and hide a drug’s problems.

Fast forward 14 years, and Dr. Peter Doshi, a University of Maryland researcher who made his name by learning that the evidence supporting the drug Tamiflu was not as apparent as we had been told (when our nation spent billions stockpiling it), wondered what could be learned by starting with the so-called “clinical study reports” from the clinical trial that put Paxil on the market.

To their credit, GSK, the company that now owns Paxil, let a tenacious set of researchers, including psychiatrists Dr. Jon Jureidini, Dr. David Healy and Dr. John Nardo, probe an even deeper level of transparency, the so-called “case report forms” — patient level paperwork stripped of all identification data — where side effects show up and are coded.

That’s where they found out how seriously suicidal the patients taking Paxil had become.

The authors stress that if a child is taking Paxil that parents should not stop the drug — there is the risk of a withdrawal syndrome in the same findings, which is why they should talk to their doctor about their concerns.

It has become fashionable for clinicians hoping to prescribe these drugs to youth and adolescents to say the side effects are overblown, and that the benefits of the drug outweigh their risks.

You will hear advocates of the pills say that children only think about suicide on the drug, but do not attempt it, or that Paxil is a unique case, but all the other antidepressants are not nearly as concerning.

But they do not have the raw data behind the trials that put those drugs on the market, and neither do the doctors who signed the published clinical trials that put those drugs on the market.

They remain the property of drug makers. It has to end. Science is numbers, and if the public is to be asked to trust the numbers, episodes like the publication this week of the news about Paxil tell us to trust, but verify.

Read More At: PostBulletin.com

The 8 Most Dangerous Medicines on Earth… Are You Taking Any Of These?

Dangerous medicine
Source: NaturalNews.com
S.D. Wells
August 30, 2016

“It’s time to take your medicine, honey.” “But Mom, it’s making me feel weird and horrible, and I’m not getting any better.” “Well, it’s what the doctor prescribed, so it’s what we have to do.” Have you ever been told to listen to your gut? There’s a reason for that. Actually, several reasons.

Many “Western” medicines are made in laboratories using chemicals and are highly experimental, and worse yet, they’re never tested on humans, except when they’re actually prescribed, applied, or injected into them. Humans are the ultimate guinea pigs in America, while Big Pharma pockets trillions in profit. How did this all come to be? Simple answer: After WWII, Nazi scientists were hired fresh out of prison to work on pharmaceuticals, vaccines, chemotherapy, and chemical food additives, in order to fuel the most insidious business on earth–allopathic medicine. It’s no conspiracy theory either. The horror that took place at the Holocaust in Germany was continued, on a lesser scale, in the United States, for money.

Think about it. There is NO OTHER REASON our U.S. based pharmaceutical companies hired convicted mass murderers to fill the highest positions at Bayer, BASF, and Hoechst. Fritz ter Meer, convicted of mass murder, served just 5 prison years, then conveniently became the chairman of Bayer’s supervisory board (yes, THAT Bayer–that makes children’s medications and the most popular aspirin). Carl Wurster of BASF helped manufacture Zyklon-B gas, the powerful pesticide used to execute millions of Jews–this freak went to work on chemotherapy, the biggest medical scam of the century. Kurt Blome, who admitted to killing Jews with “gruesome experiments,” was hired in 1951 by the U.S. Army Chemical Corps to work on chemical warfare. Get it?

In other words, Big Pharma’s evil seeds, which the FDA calls medicine, were first planted in the United States 65 years ago. Many of the “mad scientists” who tortured innocent human beings in the Holocaust were hired and promoted by U.S. Presidents to catapult what we call “Western Medicine,” and its ultimate goal of creating sickness, and then treating its symptoms for profit.

Take heed, my friends, because THESE are the 8 most DANGEROUS MEDICINES on Planet Earth. It’s called the “War Against the Weak.”

War Against the Weak

#1. SSRIs – highly experimental, never proven safe or effective, and can completely block serotonin, leading to thoughts of suicide and even homicidal and suicidal acts of horror.

#2. MMR vaccine (measles, mumps, rubella) – associated with causing autism and other central nervous system disorders and a myriad of health issues. When the LIVE measles virus gets into the body, the immune system is severely compromised, and the other chemical adjuvants and genetically modified ingredients attack the child, causing permanent and sometimes fatal results.

#3. Influenza vaccine (flu shot) – contains up to 50,000 parts per billion of mercury, in addition to formaldehyde, MSG, and aluminum. Can cause pregnant women to abort and have miscarriages

#4. Antibiotics – annihilate good gut bacteria and therefore severely decreases immune system. Doctors inappropriately prescribe antibiotics for viral infections and make matters much worse!

#5. HPV vaccine (human papillomavirus) – known to send teens into anaphylactic shock and comas. Thousands of families have sued the manufacturers for millions of dollars for chronic and permanent health damages.

#6. Chemotherapy – annihilates the immune system and often leads to the body forming new cancers, especially in the blood. Nazi scientists knew in the 1950s that chemotherapy only makes cancer temporarily recede, only to come back with a vengeance in other parts of the body! (Still, Western Medicine calls this successful)

#7. “RotaTeq” rotavirus vaccine – extremely toxic (oral) vaccine contains LIVE rotavirus strains (G1, G2, G3, G4, and P1), plus highly toxic polysorbate 80 and FETAL BOVINE SERUM. Also contains parts of porcine circovirus – a virus that INFECTS PIGS.

#8. Polio vaccine (oral and injected with needle) – It’s a cold, hard, scary fact that millions of Americans were injected with CANCER when they got the polio vaccine. Plus, the oral and nasal versions of the vaccine have been spreading polio in India and leaving many children paralyzed for life.

Sure, people are paranoid of infectious diseases and for good reason. The American medicine industry has exacerbated the WORST cases on record to scare the living hell out of everyone into injected their known carcinogens for “protection.” It’s racketeering and it’s illegal, but the vaccine manufacturers are immune to lawsuits, protected by a massive slush fund and their own secret court of law. If you or your child is severely injured by vaccines, you CANNOT sue the vaccine manufacturer. You will have to take that case to the Office of Special MASTERS of the U.S. Court of Federal Claims, which is commonly called the highly secretive “Vaccine Court.” This corrupt “court” administers a no-fault compensation program (yes, you read that correctly), that serves as an alternative to your Constitutional rights. Established back in 1986, after drug companies lost massive profits in high-profile lawsuits due to vaccines severely damaging a number of children, who suffered seizures and brain damage, linked to the DPT vaccine.

Before you EVER consider swallowing or injecting chemical toxins called “medicine” again, visit at least one Naturopathic Physician and find out if the health problem or problems are nutritional based, because odds are, they are!

Read More At: NaturalNews.com

Sources for this article include:

NaturalNews.com

Truthwiki.org

WarAgainstTheWeak.com

NaturalNews.com

http://www.npr.org

NaturalNews.com

CureYourOwnCancer.org

FoodForensics.com


NaturalNews.com

tv.naturalnews.com

blogs.naturalnews.com

NaturalNews.com

Truthwiki.org

NaturalNews.com

How Antidepressants Affect The Brain & Make People More Likely To Kill

[Editor’s Note]

For more information regarding this the countless issues with antidepressants please read:

A Mind Of Your Own: The Truth About Depression & How Women Can Reclaim Their Lives by Dr. Kelly Brogan
Toxic Psychiatry – Dr. Peter R. Breggin

Antidepressants
Source: NaturalNews.com
Ethan A. Huff
July 25, 2016

Thinking back to all the different mass shooting cases we’ve covered over the years, you may have noticed that there almost always seems to be one common denominator: the use of psychotropic medications by the perpetrators. Brain-altering antidepressant drugs are so often linked to cases of extreme violence these days that these drug-induced stupors, if you will, have been officially pathologized under the name “akathisia.”

In Greek, the term literally means “inability to sit,” and is a neuropsychiatric syndrome characterized by “subjective and objective psychomotor restlessness,” according to Dr. Fernando Espi Forcen, M.D., a Fellow of Psychosomatic Medicine at the Memorial Sloan Kettering Cancer Center. Put simply, akathisia is an unusually altered state of mind that, in some extreme cases, can cause an individual to become preoccupied with thoughts of violence, whether against himself or someone else.

The ongoing trial of Richard Henry Bain is a great example of how akathisia is gaining legal precedence as a trigger of violent crime. Though he’s being accused of first-degree murder in the infamous election night shooting in Quebec back in 2012, Bain’s lawyers say that his use of antidepressant drugs is to blame for the crime, and thus Bain shouldn’t be held legally liable.

Whether or not this is a valid defense is up to the judge in this particular case to decide. But the fact that akathisia is now a “thing” in the realm of the criminal justice system begs the question: what exactly is it? And more precisely, how is it possible for antidepressant drugs to so alter someone’s state of mind that he becomes unable to control a sudden urge to harm himself or others?

Some people metabolize drugs differently, more quickly than others

The U.S. Food and Drug Administration (FDA) admitted back in 2004 that SSRIs, SNRIs and other “new generation” antidepressants like the kind Bain was using can, in fact, worsen depression symptoms, and in some cases cause users to become suicidal or homicidal. The agency three years later issued a “Black Box” warning for these same antidepressants, suggesting that all users up to age 24 be monitored for extreme side effects including agitation, panic attacks, anxiety, hostility, impulsivity and akathisia.

As to why these drugs do this, researchers say it’s predicated upon a variance in how they’re metabolized by individual users. So-called “ultra-rapid metabolizers,” for instance, absorb the drugs’ active ingredients much more quickly than others, putting them at a higher risk of experiencing wild behavioral and mental fluctuations. There’s also the genetic factor; certain gene variations can precipitate variances in how antidepressant drugs affect users’ brain chemistry.

“Fast-changing levels of psychotropic substances, up or down, can cause behavioural changes as the neurotransmitters in the brain react to reach some equilibrium,” a paper entitled Study 329 explains about the chemical process. “This phenomenon makes starting and stopping medication the most dangerous times for suicide and violence, but both can happen at any time, with stress, provocation, dose change, addition or subtraction of a medication.”

Antidepressants operate within very specific biological pathways, the balances of which can easily be thrown off, depending on a person’s unique biological and genetic makeup. Antidepressants have also been shown to cause long-term brain damage, affecting the intermolecular interactions in such a way as to completely alter brain chemistry, possibly permanently.

Read More At: NaturalNews.com