Falsified drug studies led to millions of children receiving dangerous antidepressants

Depression
Source: ProjectCensored.com
April 6, 2016

In 2001, the pharmaceutical company SmithKline Beecham (now GlaxoSmithKline) published a trial known as Study 329, which claimed that the drug paroxetine – known as Paxil or Seroxat – was “generally well tolerated” and that it helped cure depression in children and adolescents. This led to some two million youngsters being prescribed the pill in the next year alone.

But the study ignored the fact that the drug may cause serious side effects, including suicide. Re-analysis of Study 329 by a team of independent researchers showed the drug was no more effective than a placebo, and that the risk of harm was significant, with at least 12 out of 93 children taking the drug developing suicidal thoughts. GlaxoSmithKline was fined $3 billion for one of the biggest frauds in American healthcare history.

This is but one example of pharmaceutical industry influence shaping the outcome of scientific research. A recent study, published in the Journal of Clinical Epidemiology, evaluated 185 meta-analyses, and found that one third of them were written by pharma industry employees, who were 22 times less likely to have negative statements about a drug than unaffiliated researchers. Almost 80 percent of the studies had some sort of industry tie, either through sponsorship (funding of the study), or conflicts of interest, where one or more authors were either industry employees or independent researchers receiving industry support (speaking fees, grants, etc.).

In a 2006 study examining industry impact on clinical trials of psychiatric medications, industry-sponsored trials reported favorable outcomes 78% of the time, compared with 48% in independently funded trials. Antidepressants are one of the largest pharmaceutical markets, yet it is likely that the problem of scientific fraud extends to other drugs and vaccines. The need for oversight (government and industry) is increasingly obvious.

Read More At: ProjectCensored.com
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Sources:

Sophie Borland, “Global drug giant GSK ‘published a flawed study which led to millions of children being wrongly prescribed dangerous antidepressants’.” Daily Mail. September 17, 2015, http://www.dailymail.co.uk/health/article-3238108/Global-drug-giant-GSK-published-flawed-study-led-millions-children-wrongly-prescribed-dangerous-antidepressants.html

Kate Kelland, “Analysis of Antidepressant Paxil Finds Data on Teen Risk Was Held Back.” Scientific American. September 17, 2015, https://www.scientificamerican.com/article/analysis-of-gsk-s-paroxetine-antidepressant-finds-key-data-was-held-back/

Stephen Luntz, “Antidepressant Trial Failed To Mention Numerous Suicide Attempts.” IFL Science. September 21, 2015, http://www.iflscience.com/health-and-medicine/study-antidepressant-safety-didnt-report-suicide-attempts

Roni Jacobson, “Many Antidepressant Studies Found Tainted by Pharma Company Influence.” Scientific American. October 21, 2015, http://www.scientificamerican.com/article/many-antidepressant-studies-found-tainted-by-pharma-company-influence/

Paul John Scott, “Why should it take 14 years to learn a drug’s safety risks?” Post-Bulletin. September 21, 2015. http://www.postbulletin.com/life/health/why-should-it-take-years-to-learn-a-drug-s/article_50f181c5-b6d8-5776-8df9-b0acf5b3108f.html

University of Adelaide. “Antidepressant For Adolescents Was Misrepresented As Safe.” AsianScientist. September 25, 2015. http://www.asianscientist.com/2015/09/health/adelaide-paroxetine-depression-riat/

Student Researcher: Adaeze Iroka, San Francisco State University

Faculty Evaluator: Kenn Burrows, San Francisco State University

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Seen Any Big Pharma Drug Advertisements Lately? – Why Individuals Must Be Highly Skeptical Of Big Pharma Drug Pushing

BigPHarma
TheBreakaway
Zy Marquiez
April 6, 2016

Out of all countries in the world, the only places where advertising drugs to consumers is legal, is in the United States, and in New Zealand.  You read that correct.  In all but two countries it is illegal to promote/advertise drugs directly to consumers.  

Many people do not know this, and for good reason.  The pharmaceutical companies would prefer people not realize what’s illegal elsewhere, because it would quickly show incisive individuals something is amyss.  People would immediately question the veracity of the situation.

Why is this important?  Because that law is in place to protect individuals from the highly specialized, and yet misleading advertising of all drugs.

Incomplete because, as Dr. Brogan notes in her landmark book, A Mind Of Your Own:

“…only two studies are required for FDA licensure of most pharmaceuticals, essentially leaving the population to participate in a post-marketing experiment in which adverse effects – casualties – are monitored passively.  It’s a fabrication of science to think these drugs have a place in medicine, what is meant to be the art of healing.” [1][Bold Emphasis Added]

Brogan continues outlining how efficient Big Pharma advertising is:

“It’s been calculated that DTCA [drug-to-consumer advertising] is responsible for nearly half (49 percent) of requests for drugs.  And fully seven out of ten times doctors prescribe based on appeal by patients who learned through their computers and televisions that they have an “imbalance” that must be fixed with a pill.”[2][Bold Emphasis Added]

More disturbingly, there is no extensive long term studies carried out to clear Big Pharma drugs before getting approval.  And these very drugs that have not been tested in any true long term settings continued to be doled out by the Billions per annum. 

Getting to the core of the matter, Dr. Brogan elaborates:

Their patients have never consented to the long-term effects of these medications because pharmaceutical research is, by nature, short term.  There is no incentive on the part of the pharmaceutical  companies to take a good look at what happens to the average individual when she takes a medication for a decade or so.”[3][Bold Emphasis Aded]

The issue has gotten so bad, some doctors are even calling for a ban of this duplicitous practice.

With so much at stake – more than just health, people’s lives in fact – why is it that so many people continue running around the hamster wheel expecting change to take place in a corrupt for-profit system?  Is it blind trust?  Indoctrination?  Or is it more?

Either way, those particular laws that other countries have implemented, have been excluded from American Law.  This is quite concerning, giving the tens of millions taking medications in the United States.

In an environment which fosters duplicitous actions by corporations at the expense of the individual, what can one do?

Do your research.  Take charge of your health.  Read as much as possible about the disease – or health issue/concern – that you have.  Then read some more.  Don’t allow yourself to become one of the hundreds of thousands of people that lose their lives by preventable medical mistakes.[4]

Do not allow yourself or your family/friends or anyone to become a statistic. 

In the end, our health, just like our lives, can ultimately be in our hands, or in the hands of those that just seek to profit from us at any expense.  Because after all, cures don’t make money.  Only disease does.

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Sources & References

[1] Kelly Brogan M.D., A Mind Of Your Own – The Truth About Depression, pg. 49
[2] Ibid., p. 52.
[3] Ibid., p. 35.
[4] Medication Errors Injure 1.5 Million People & Cost Billions Of Dollars Annually
http://www.naturalnews.com/020515_drugs_drug_health.html
http://www.reuters.com/article/us-pharmaceuticals-advertising-idUSKCN0T62WT20151117