Dr. Kelly Brogan – Depression: Busting Myths & Finding Answers

TheBreakaway
Vid Source: SacredScienceDoc
Zy Marquiez
April 3, 2017

Dr. Kelly Brogan’s book, A Mind Of Your Own – The Truth About Depression, was one of the top 3 Books of the Year for 2016 at The Breakaway. The depth and scope of the information presented within that book was not unlike what Dr. Peter Breggin did in his quintessential Toxic Psychiatry.

Interviewed below, Dr. Brogan goes into many of the pervasive myths taking place within the field while offering her insights on issues within psychiatry.
__________________________________________________________________________

To learn more about alternative ways of treating depression and other conditions, visit us at http://www.thesacredscience.com/.

A few months ago we had the chance to sit down with Dr. Kelly Brogan, a NYC-based psychiatrist who’s offering a new approach to healing.

Trained in the ways of Western Medicine, but having seen first hand the way the system has evolved into what it is today, under the influence of pharmaceuticals, she is shining the light on some very important truths and turning everything we know about the topic of depression on its head.

The question “is pain and suffering a good thing?” might seem like something only the Dalai Llama would ask, but in our interview, Kelly discusses how going through tough times and hardships actually make us stronger, and equip us with the tools to combat even harder struggles down the line.

If you’re interested in learning about the true meaning of depression and how to treat it the right way, or what we may be losing by the death of the rites of passage, or why all mainstream media outlets said no to sharing the information in her new book “A Mind of Your Own,” even though it was backed by one of the biggest names in publishing, you should definitely watch this interview.

The knowledge she shares will change the way you think about what you or your loved ones have gone through, or are going through now, and more importantly, how to move forward in the best way possible…

Surprising Side Effects of Tylenol

Surprising Side Effects of Tylenol
Source: GreenMedInfo.com
Dr. Kelly Brogan
March 5, 2017

Originally published on KellyBroganMD.com

You know Tylenol can relieve a headache, but are you aware it can cause other side effects, such as increased risk of death or heart toxicity?

Tylenol: Helping or Hurting?

Have you ever popped a Tylenol to push through that annoying headache and get on with your day? Most of us have. Each week, millions of Americans take one of the 600 medicines that contain acetaminophen, Tylenol’s active ingredient, for various aches and pains. Acetaminophen is the most common drug ingredient in the US, but this ‘harmless drug’ is linked to over 110,000 injuries and deaths per year.

How can Tylenol, which is doled out like candy, be bad for you? Amazingly, no one really knows how acetaminophen works [1], but people do know that this drug gets to your brain. Tylenol in your brain is concerning because it depletes glutathione [2], an antioxidant that is especially necessary for brain health. Our bodies depend on antioxidants to balance oxidative damage and inflammation. If you’re popping a Tylenol with your morning antioxidant-rich KB Smoothie, Tylenol may rob you of the smoothie’s benefits!

Beyond Liver Damage

Most people have heard that Tylenol can damage the liver (has anyone ever drunkenly warned you to take a Motrin, not a Tylenol, to prevent a hangover?). But since everything in our bodies is connected, it’s not surprising that Tylenol can do damage beyond your liver. A recent study showed that people who took Tylenol had increased risks of death, heart toxicity, gastrointestinal bleeding, and kidney damage [3]. Importantly, people who took more Tylenol suffered more damage.

It’s also scary how Tylenol affects mood. After swallowing 1000 mg of Tylenol, people exhibited less empathy and blunted positive emotions. For reference, 1000 mg is two extra-strength Tylenol tablets, and the ‘safe’ range is 3000 mg per day. This means that popping two Tylenols can affect you physically and emotionally!

If you’re pregnant or looking to become pregnant, please be especially careful about taking Tylenol. Research has shown that children exposed to acetaminophen in the womb had behavioral, communication, and motor skill problems. Another study linked prenatal acetaminophen exposure with increased ADHD-like behaviors and medication use.

What about other painkillers?

Hopefully you’re convinced to think twice before taking a Tylenol, but what about other pain-relievers like Motrin, Aleve, or Advil? These non-steroidal anti-inflammatory drugs (NSAIDs) must be safe, since thirty million people take them every day! Not so fast…

Women who recognize the importance of hormonal balance should be wary. NSAIDs can mess with ovulation, especially progesterone levels, after only 10 days of use [4]. Additionally, NSAIDs injure the small intestine; in one study, 71% of NSAID users showed small intestinal damage, compared to 10% of non-users [5]. Damaged intestines can lead to intestinal permeability, or “leaky gut.” Leaky gut has been linked to depression, ADHD, and allergies.  NSAIDs can cause leaky gut [6] and harm your microbiome, the trillions of beneficial bacteria that live in and on us. Disrupting our bacteria can do more damage than we realize!

How can I relieve my headache?!

Now that you know the surprising dangers of Tylenol and other NSAIDs, what should you take for headaches and other aches and pains? Turmeric, the yellow root found in curry powder, contains a powerful anti-inflammatory and pain reliever called curcumin. This has been used in Ayurvedic and Chinese medicine as a treatment for pain, digestive disorders, and wound healing for centuries. Many studies show the beneficial effects of curcumin; curcumin works as well as ibuprofen to alleviate pain from knee osteoarthritis [7] and PMS [8]. Next time you have a headache, try 1-2 grams of curcumin – or a turmeric latte!

 

Dr. Kelly Brogan- Depression & Anxiety Tips for Women

TheBreakaway
Zy Marquiez
March 6, 2017

Dr. Kelly Brogan is an Integrative psychiatrist (trained at MIT and Cornell) who came on the podcast to chat about her new book, A Mind of Your Own: The Truth About Depression and How Women Can Heal Their Bodies to Reclaim Their Lives.

For those seeking more information please read Dr. Brogan’s landmark book:

A Mind Of Your Own – The Truth About Depression & How Women Can Heal Their Bodies by Dr. Kelly Brogan

Source: High Intensity Health

Key Takeaways from the interview:

01:58 “Before I stopped prescribing, I never once cured a patient” Dr. Brogan was a traditional psychiatric doctor from a traditional family. The goal of traditional psychiatry is to keep you functioning and to suppress symptoms. Many mental illnesses are not valid illnesses or diseases. They are symptoms. Most outpatient psychiatrists do not run basic blood panels on their patients to rule out known reversible causes, like B12 deficiencies. She began recommending fish oil, Rhodiola rosea, and other supplements to her patients on pharmaceuticals. Then she read an expose’ by Robert Whitaker called The Anatomy of an Epidemic, which brought her to a lesser known body of science. She stopped using pharmaceuticals and began to cure patients. Her goal is to not only get her patients off of their prescriptions, but to give them the tools to not need to see her.

05:45 Depression Medication Paradox: Practitioners and the lay person (via direct to consumer advertising) are taught that depression is a discrete disease that is likely heritable and is a result of a chemical imbalance, often a serotonin imbalance. There are antidepressant medications that are serotonin reuptake enhancers as well as other that serotonin reuptake inhibitors, and others that have little impact upon serotonin, but impact norepinephrine and dopamine. Trials show comparable efficacy in non-psychiatric medications like beta blockers or thyroid hormone.

07:51 Do Such Disparate Medications Work? Dr. Brogan says that these medications do not work. The reported efficacy is 30%. There is much unpublished literature. A psychiatry study found that 37 of 38 negative studies used to approve 12 antidepressants were not published because they were negative. When you adjust for active placebo effect, these medications have negligible efficacy.

09:14 Antidepressants: Active Placebo Effect: It is the recruitment of bodily beliefs about your being sick and there being a chemical fix. When you are in a trial, you are told that if you receive the treatment, you may get dry mouth, diarrhea, or headache. The placebo might be a sugar pill. When you start to get the side effects, you tell yourself that you are in the treatment group and you believe that you will get better. A follow up study of people who were successfully treated with Prozac were told that they would be randomized to placebo or continue on the same does that cured them. Both groups became depressed. The power of belief or expectancy is a very important and complex factor.

11:56 Long Term Effects: There is not a single study that suggests that being treated with antidepressants for any psychiatric disorder results in improved long term functioning or improved long term outcomes. According to the WHO, depression is the number one cause of disability, yet we have more prescribing of treatment than ever before. This should be inversely proportional. What if the treatment is inducing disability and a chronic disorder that might have otherwise been a reversible single episode phenomenon? It is time to re-examine the theory that depression has anything to do with brain chemicals.

13:07 The Cytokine Theory of Depression: The primary literature is beginning to support the idea that it could be a body-wide, system-wide phenomenon. It comes down to the mismatch of lifestyle with our over 2.5 million years of what our genes have come to expect. This theory asks what we can do to better align our lifestyle with those of our ancestors so the alarm systems in the body, inflammatory systems, and immunological mechanisms, are not on constant high alert. Depression is a Symptom

15:41 Diet vs Prozac: Prozac will not produce clinical effects, just side effects, for 6 to 8 weeks after treatment starts. Diet will produce positive effects within 30 days.

The Truth About Depression with Dr Kelly Brogan

Source: The Spa Dr.
Dr. Kelly Brogan M.D.
February 27, 2017

Today my guest guest is holistic psychiatrist Dr. Kelly Brogan, and we’re covering The Truth about Depression. Dr. Brogan is an author of the new book “A Mind of Your Own” [Review Here] and co-editor of the landmark textbook “Integrative Therapies for Depression”.

She completed her psychiatric training and fellowship at NYU Medical Center after graduating from Cornell University Medical College and has a B.S. from MIT in Systems Neuroscience.

She is board certified in psychiatry, psychosomatic medicine, and integrative holistic medicine. She has specialized in a root-cause resolution approach to psychiatric syndromes and symptoms. She is also a mother of two children.

Dr. Brogan covers some pretty shocking information about the conventional approach to depression. She explains what the root cause of depression is which is very different from what other psychiatrists are saying. And she discusses a more a holistic approach that is surprisingly similar to what I talk about with addressing skin issues.

Topics discussed today include:

Dr. Brogan had a very traditional medical background and started specializing in women’s psychiatry
While working with pregnant women, she realized she wouldn’t be comfortable taking some of the medications these women were prescribed.  After she had her own baby, she was diagnosed with Hashimoto’s disease and she realized there had to be a better way to deal with it.  She consulted a naturopath, and started supplementation and dietary changes.
Within six months, these changes helped her numbers go to a normal range.  The fact that these lifestyle changes put what would normally be a lifelong disease into remission raised some flags with Dr.Brogan.  She began diving into literature about nutrition and pharmaceutical products and psychiatric medications.  Long term use of antidepressants result in worse outcomes than never taking it.  Depression is the number one worldwide cause of disability.

Shouldn’t more treatment mean less disability?  Dr. Brogan started wondering about the effectiveness of these treatments and started asking patients if they would like to wean off of the medication.  That is when she noticed how habit forming these medications are.  She believes people should have all of the information before they go on these drugs, if at all
A Mind of Your Own is 10 years of Dr. Brogan’s research curated into one book.

We discuss SSRI’s, who takes them, and what they are supposed to do
Depression as an inflammatory disorder, symptoms may be there for a reason
Lifestyle interventions that can help with these issues
Eliminate processed foods
Eat organic produce and pastured meat products
Cut out grains, legumes, and soy, especially at the beginning
Meditation – Kundalini Yoga
High Intensity Low Volume Exercise – Once a week
Detox your environment, coffee enemas, skin brushing
Coming off medicine needs to be done slow and strategically

Key Takeaways:

Our bodies are interconnected as a whole. Healthy lifestyle choices can as effective or more effective in treating an array of health issues including depression and inflammation. Dr. Brogan has curated information and evidence supporting this in her new book, A Mind of Your Own.

Mentioned on today’s show:

A Mind of Your Own
Integrative Therapies for Depression
Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America
SSRI Stories
Antidepressants and the Placebo Effect by Irving Kirsch

22 Disturbing Facts Big Pharma Doesn’t Want You To Know

bigpharmabigmedica
TheBreakaway
Zy Marquiez
February 10, 2017

“It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine.”
–Marcia Angell, MD, New York Review of Books, 2009

Below follow 22 facts, each of which is individually disturbing enough, but when taken in conjunction paint a very ominous picture of the state of the medical establishment in America.

Embedded within the bowels of Big Pharma lie little known details most individuals are unaware of.

Most of these details rarely get reported by the mainstream media, and when they do, the slant is always in favor of Big Pharma, and if not, what the individual gets is a limited hang out, which barely even amounts to the ghost of the truth.

The following are some of the many issues that do not get to see the light of day, but should be spoken at length about:

#1: Did you know that the FDA frequently misleads the public regarding long term studies and health?

According to Dr. Peter Breggin, in his landmark book Toxic Psychiatry [review here]:

“People assume that FDA approval and the widespread distribution of a drug – with many patients taking it for months or years – means that longterm studies have found it safe in regard to side effects, drug interactions, dependency, addition, and withdrawal.  Thus, FDA approval grossly misleads the public, lulling it into an unfounded security.

The PDR admits that Prozac’s effectiveness has not been tested in controlled trials of “more than 5 or 6 weeks” and that “long-term” usefulness has therefore not been demonstrated.”[Bold Emphasis Added][1]

#2: Did you know that the U.S. and New Zealand are the only countries which allow drug companies to advertise directly to consumers?

Prior to 1997, there was a ban in place that restricted pharmaceuticals from advertising to consumers – known as drug-to-consumer-advertising, or DTCA- but this ban was removed, to the detriment of the populace.[2]

Why is this important?  Because that law was in place to protect individuals from the highly specialized, and yet misleading advertising of all drugs.

#3:  The great majority of prescription drugs sold is due to DTCA.  As Dr. Kelly Brogan notes in her landmark book, A Mind Of Your Own, The Truth About Depression [review here], in which she touches upon this specialized advertising:

“It’s been calculated that DTCA [drug-to-consumer advertising] is responsible for nearly half (49 percent) of requests for drugs.  And fully seven out of ten times doctors prescribe based on appeal by patients who learned through their computers and televisions that they have an “imbalance” that must be fixed with a pill.”[3][Bold Emphasis Added]

#4:  Coupled with the already disturbing above information, and with prescription drugs being doled out at 4 Billion per annum[4], it’s no wonder that Medical Errors are the third leading cause of death.[5]According to a new John Hopkins study, which is covered by the Washington Post:

“Their analysis, published in the BMJ on Tuesday [, shows that ‘medical errors’ in hospitals and other health care facilities are incredibly common and may now be the third leading cause of death in the United States — claiming 251,000 lives every year, more than respiratory disease, accidents, stroke and Alzheimer’s.”[6][Click here for the study named Medical Error – The Third Leading Cause Of Death In The US]

#5:  Unsurprisingly, given how Big Pharma & Big Medica have had no qualms in overstepping traditional boundaries, it’s no wonder that in many instances money from pharmaceutical companies sway Doctors’ prescriptions, which shows the serious conflict of interest.[7]

As Dr. Mercola elucidates:

“Not only was the receipt of drug-company money associated with a higher percentage of brand-name drug prescriptions, but the prescriptions rose with the amount of money received.”[Bold Emphasis Added]

#6:  Did you know, the FDA only requires two studies for drugs to be approved?

“…only two studies are required for FDA licensure of most pharmaceuticals, essentially leaving the population to participate in a post-marketing experiment in which adverse effects – casualties – are monitored passively.  It’s a fabrication of science to think these drugs have a place in medicine, what is meant to be the art of healing.”[8]

But there’s more.  Most drug research is in fact short term.  Dr. Brogan cautions:

Their patients have never consented to the long-term effects of these medications because pharmaceutical research is, by nature, short term.  There is no incentive on the part of the pharmaceutical companies to take a good look at what happens to the average individual when she takes a medication for a decade or so.”[9][Bold Emphasis Added]

#7:  This hyper-drugging of the populace has lead to prescription drugs in fact being 16,400% deadlier than terrorists.  But you won’t hear that in the mainstream media.[10]

#8:  Not only is our corrupt for-health for-profit medical system unsurprisingly the most expensive in the world[11], but our life expectancy is worse than that of a third world country.[12]

#9:  Heart surgery is 70 times more expensive in the US.[13]

#10:  Of course, with billions of prescriptions being filled yearly, it’s no wonder that 70% of Americans take prescription drugs.[14]

#11:  In fact, expensive treatment requests have predictably gotten so bad that Doctors are even calling for a ban for the duplicitous practice of DTCA.[15]

#12:  A large study, which was published in The Lancet, further debunks high cholesterol myths, admitting statin drugs are essentially worthless.[16]

#13:  Another study shows that combining multiple childhood vaccines isn’t safe, according to an article in the Journal Of American Physicians and Surgeons.[17]

#14:  The same statin drugs that were found to be worthless against cholesterol, are now going to be used as anti-cancer drugs.  You can’t make this stuff up![18]

#15:  Although the US has merely 5% of the world’s population, it consumes 80% of the world’s pain killers.[19]

#16:  A great portion of this is in large part to what is called “Disease Mongering” and the creation of disease.[20]

#17:  Pharmaceutical companies Genentech and OSI Pharmaceuticals have even been caught concealing adverse effects of drugs, and were ordered to pay a $70 million dollar fine.[21]

#18:   America has the worst infant mortality rate of all developed nations.  Let that disturbing fact sink in.[22]

#19: Since 1986 Big Pharma has had liability shielding preventing it from being prosecuted for endangering public health[23].  And some wonder why the medical establishment is so corrupt.

#20: Not long ago, medical conglomerate, Pfizer, paid over $2 BILLION Dollars for criminal and civil charges due to illegally promoting the use 4 of its drugs. [24]

#21: Merely months ago, a study proving that vaccinated children are 3 times more likely to be diagnosed with autism and other neurological issues was banned from the internet.[25]

#22:  Because of all of the reasons mentioned above, and more, Americans are spending over $30 billion dollars in out-of-pocket costs on alternative health[26].  Thankfully!

This overall pattern of dwindling care, that’s overly expensive, and only serves to fill the coffers of Big Pharma will only change when individuals quit buying in to the propaganda from the medical establishment.

And for all the technology, public schooling, and billions spent, our medical system isn’t even top 3 in the world, and the statistics prove it.

Instead of purchasing health insurance, perhaps individuals should focus on attaining health assurance.

The system in its current state sees people as nothing but cash cows, and the sicker they are, the more money they make.  And they also aren’t coming up with cures since that, also, will cut into their profits.
One must wonder, seeing that they have no virtues and are willing to throw the people under the bus with lies and fraud, what else are they willing to do?

Take control of your health, while you still got time.

Education will eviscerate ignorance; nutrition will beat disease; corruption will continue to be exposed; but only if the individual chooses to make it so.

Be mindful, stay aware.

Individuals can go with the flow, and take the tides as they come, or they can choose to rise to the occasion.

Pierce the veil.

Cast light on the shadows.

And become the solution you’ve always waited for.

________________________________________________________________
Sources & References:

[1] Dr. Peter R. Breggin, M.D., Toxic Psychiatry, pp. 168-169
[2] Dr. Joseph Mercola, The Great Bird Flu Hoax, p. 39.
[3] Dr. Kelly Brogan M.D., A Mind Of Your Own – The Truth About Depression, p. 52.
[4] http://www.naturalnews.com/037226_drug_prescriptions_medical_news_pills.htm
[5] https://www.washingtonpost.com/news/to-your-health/wp/2016/05/03/researchers-medical-errors-now-third-leading-cause-of-death-in-united-states/?utm_term=.d262ea291b26
[6] http://www.bmj.com/content/353/bmj.i2139
[7] http://articles.mercola.com/sites/articles/archive/2016/04/13/doctors-receiving-pharmaceutical-money.aspx
[8] Dr. Kelly Brogan M.D., A Mind Of Your Own – The Truth About Depression, p. 49.
[9] Ibid., p. 35.
[10] http://www.naturalnews.com/009278.html
[11] http://www.zerohedge.com/news/2014-06-22/us-healthcare-snapshot-most-expensive-yet-worst-developed-world
[12] http://www.salon.com/2013/10/22/life_expectancy_in_america_rivals_third_world_partner/
[13] http://www.zerohedge.com/news/2013-07-29/what-does-heart-surgery-really-cost-and-why-it-70-times-more-expensive-us
[14] http://www.cbsnews.com/news/study-shows-70-percent-of-americans-take-prescription-drugs/
[15] http://www.reuters.com/article/us-pharmaceuticals-advertising-idUSKCN0T62WT20151117
[16] http://www.naturalnews.com/054388_statin_drugs_medical_myths_Big_Pharma.html
[17] https://globenewswire.com/news-release/2016/06/14/848493/0/en/Combining-Multiple-Childhood-Vaccines-Not-Safe-According-to-Article-in-the-Journal-of-American-Physicians-and-Surgeons.html
[18] http://www.naturalnews.com/054707_statins_cancer_treatment_Big_Pharma.html
[19] http://www.dailymail.co.uk/news/article-2142481/Americans-consume-80-percent-worlds-pain-pills-prescription-drug-abuse-epidemic-explodes.html
[20] http://www.huffingtonpost.com/dr-larry-dossey/big-pharma-health-care-cr_b_613311.html
[21] http://edition.cnn.com/2016/06/07/health/genentech-lung-cancer-drug-settlement/index.html
[22] https://www.washingtonpost.com/news/wonk/wp/2014/09/29/our-infant-mortality-rate-is-a-national-embarrassment/?utm_term=.9f6b6a036ca9
[23] http://www.nvic.org/NVIC-Vaccine-News/November-2016/end-pharma-liability-shield-protect-human-rights.aspx#_edn79
[24] http://edition.cnn.com/2010/HEALTH/04/02/pfizer.bextra/
[25] http://investmentwatchblog.com/study-proving-vaccines-cause-autism-banned-from-internet/
[26] http://www.usatoday.com/story/news/2016/06/22/study-americans-spend-billions-non-conventional-health-approaches/86200430/

What’s the Harm in Taking an Antidepressant?

Source: KellyBroganMD.com
Dr. Kelly Brogan M.D.
November 8, 2016

what's-the-harm

We know that all drugs have side effects. That’s just part of the deal right? But is it really possible that an antidepressant can cause a sane person to act like a cold-blooded criminal?

I imagined my audience would be wondering as much as I arrived to an unseasonably chilly day at King’s College in London. I was there to share what I have learned about the medications that I so dutifully and faithfully prescribed during the early part of my career, and also about the deep potential for healing depression in simple, safe ways, according to the latest science.

The day before my flight, I had received an email from a man who I would choose to invite on stage with me that day. His name is David Carmichael and he wrote:

“I took the life of my 11-year-old son Ian on July 31, 2004 in a Paxil-induced state of psychosis and was charged with first degree murder. I was judged to be “not criminally responsible on account of a mental disorder” in September 2005 and received an absolute discharge from the forensic psychiatric system (in Ontario, Canada) in December 2009. I’ve been off all prescription drugs since September 2010. Prior to our family tragedy, I was a physical active sports consultant with no history of violence or mental illness.”

He told an audience of clinicians and patients, that day, about how it is that a normal citizen, prescribed a seemingly safe medication for work-related stress, goes on to commit a heinous act of violence against his beloved child. This academic classroom was heaving with grief when he finished his description of events.

This must be rare, right? Totally anomalous?

Wrong.

It has become my contention that the Russian Roulette that is played with each new prescription of psychotropic medication violates the physician’s most primal tenet – first do no harm – and does so in the absence of anything approximating informed consent.

Violence as a Side Effect?

Thankfully, we are often given multiple chances to wake up to a greater truth. It’s becoming easier than ever. With grassroots platforms like madinamerica.com, the information is out there, when you are ready to look beyond main stream media to what the real victims are claiming.

The truth about antidepressants and violence is also in the most recently published literature, including a critical review, hot off the press, by Carvalho et al where the authors dive into the research on the supposed safety of SSRIs and SNRIs. In this document, they present an evidence-based horror menagerie of ways in which a simple antidepressant can derail your life if it doesn’t take it. Leaving patients with new medical diagnoses, antidepressants prescribed often for difficult transitions in life like divorces and deaths, carry documented risks that your doctor cannot possibly tell you about because if they knew of them, they would put down their prescription pad immediately.

Let’s take a tour. Neatly summarized here, the adverse effects of antidepressants can sound like that droning voice in TV ads that we are inured to because we have been told these “side effects are rare, and outweighed by the benefits.”

But the benefits are shockingly limited so, let’s take a closer look at those side effects…

harm image

The Risks That Made Me Quit Prescribing

Having always represented antidepressants as safe and effective to my patients, I put down my prescription pad after learning 3 facts about psychiatric medications:

  • They result in worse long-term outcomes [1]
  • They are debilitatingly habit forming [2] [3] [4]
  • They cause unpredictable violence [5] [6]

These insights were apparently just the tip of the iceberg. Several years into the horror stories of patient experiences and new relationships with grassroots activists, I am left wondering. What on earth are these meds? How could biochemistry have ever manifested molecules capable of derailing, distorting, and suppressing the human experience to this extent?

With more unknowns than knowns at this point, the signal of harm is growing and patient alignment with this model of care, diminishing.

I pulled some choice phrases from the paper for your further enlightenment below but suffice it to say that many of these side effects are major gamechanging problems if not life-ending tragedies that render the placebo-level performance of these medications totally unacceptable.

Gut disturbance: “Some of the most frequently reported side effects associated with the use of SSRIs and serotonin noradrenaline reuptake inhibitors (SNRIs) include nausea, diarrhea, dyspepsia, GI bleeding and abdominal pain.”

Liver toxicity: “Two main mechanisms may be involved in antidepressant- induced liver toxicity, namely a metabolic component and/or an immuno-allergic pathway. A hypersensitivity syndrome with fever and rash as clinical manifestations, as well as with autoantibodies and eosinophilia, and a short latency period (1–6 weeks) point to a predominantly immunoallergic pathophysiological mechanism, whereas a lack of hypersensitivity syndrome and a longer latency period (i.e. 1 month to 1 year) points to an idiosyncratic metabolic mechanism.”

Weight gain: “Notwithstanding the complexity of the clinical scenario, compelling evidence indicates that the use of most antidepressants may increase weight in a significant proportion of patients.”

Heart problems: “SSRIs and SNRIs may promote a decrement in heart rate variability (HRV). Although the impact of the effects of antidepressants on HRV remains to be established, data indicate that a lower HRV is a significant predictor of incident cardiovascular events.”

Urinary problems: “SSRIs can cause urinary retention by acting on central micturition pathways. Serotonin may increase the central sympathetic outflow leading to urinary storage, and at the same time inhibits parasympathetic flow, which affects voiding.”

Sexual dysfunction: “…a significant body of data shows that antidepressants may differentially affect sexual function in multiple aspects, leading to reductions in libido, arousal dysfunction (erection in males and vaginal lubrication in females) and orgasmic dysfunctions.”

Salt imbalance: “The mechanisms of SSRI-induced hyponatremia remain incompletely elucidated, but these agents can act by either increasing the release of antidiuretic hormone (ADH) or increasing the sensitivity to ADH resulting in a clinical picture similar to the syndrome of inappropriate secretion of ADH.”

Osteoporosis/Bone weakening: “The use of SSRIs has been associated with a reduction in bone mineral density (BMD) and a consistent higher risk of fractures.”

Bleeding: “All serotonergic antidepressants have been associated with an increased risk of bleeding. The most likely mechanism responsible for these adverse reactions is a reduction of serotonin reuptake by platelets, although other mechanisms have also been implicated.”

Nervous system dysfunction: “All kinds of EPS [extrapyramidal symptoms] are seen in patients taking antidepressants, but akathisia appears to be the most common presentation followed by dystonic reactions, parkinsonian movements and tardive dyskinesia…Headache was one of the most common side effects associated with the use of antidepressants in a large retrospective cohort of adolescents and adults.”

Sweating: “Most studies indicate that approximately 10% of patients on SSRIs may develop excessive sweating, although the incidence may be higher for paroxetine.”

Sleep disturbances: “The SSRIs and venlafaxine are associated with increased REM sleep latency and a reduction in the overall time spent in the REM phase while sleeping.”

Mood changes: “Many patients taking SSRIs have reported experiencing emotional blunting. They often describe their emotions as being ‘damped down’ or ‘toned down’, while some patients refer to a feeling of being in ‘limbo’ and just ‘not caring’ about issues that were significant to them before…Furthermore, an activation syndrome in which patients taking antidepressants may experience anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness and impulsivity in the first 3 months of treatment may ensue.”

Suicidality: “The incidence of suicide and attempted suicide has been a frequently underreported adverse outcome across antidepressant RCTs.”

Overdose toxicity: “Patients with MDD are at increased risk of suicide and overdosing of prescribed medications is a common method used to attempted suicide.”

Withdrawal Syndrome: “These symptoms include flu-like symptoms, tremors, tachycardia, shock-like sensations, paresthesia, myalgia, tinnitus, neuralgia, ataxia, vertigo, sexual dysfunction, sleep disturbances, vivid dreams, nausea vomiting, diarrhea, worsening anxiety and mood Instability.”

Eye disease: “A subset of patients taking SSRIs reports nonspecific visual disturbances…SSRIs may increase intraocular pressure and lead to the emergence of angle-closure glaucoma…A nested case-control study found a higher likelihood of cataracts after exposure to newer generation antidepressants.”

Hormonal imbalance: “Long-standing increases in peripheral prolactin levels are occasionally observed in patients using ADs, including SSRIs [208] ; hyperprolactinemia may have deleterious health consequences (e.g. a decrease in BMD [bone mineral density] and hypogonadism).”

Pregnancy/Breastfeeding risk: “Most of the data describing the presence of birth defects associated with SSRI use have been based on observational studies and drug registries. Therefore, the clinical significance of these data is questionable.”

Cancer risk: “Preclinical studies have found that antidepressants can increase the growth of fibrosarcomas and melanomas, and may also promote mammary carcinogenesis.”

Whew! Now that’s depressing. And why don’t you know about these? Because your doctor doesn’t. I recently learned of a patient who was prescribed an antidepressant simultaneous to an antibiotic “just in case the antibiotic caused depression or mood changes”. We are trained to treat these medications as a “why not” application of pharmacology, and the truth is that, as the authors state:

the history of toxicology reminds us vividly of the lag that often occurs between the first approval of a drug for use in humans and the recognition of certain adverse events from that drug.”

Taking these risks seems all the more unecessary with the robust outcomes of lifestyle medicine – multimodal, multi-tier interventions that are low cost, immediately available, and side effect free. As the authors conclude:

The findings of this review suggest that long-term treatment with new generation ADs should be avoided if alternative treatments are available.”

I would have to agree and affirm that these “alternative” treatments are indeed available. These treatments offer not only resolution of symptoms and elimination/avoidance of meds, but an entirely new experience of self. This is not about getting “back to normal,” it’s about integration, evolution, and vitality. I’ve been working for several years to make self-healing toolkits available to everyone considering an antidepressant or looking to come off of one for less than the price of one doctor visit. Check it out!

[1] http://www.power2u.org/downloads/AnatomyofanEpidemic-SummaryofFindings-Whitaker.pdf
[2] https://www.karger.com/Article/FullText/371865
[3] http://www.madinamerica.com/psychiatric-drug-withdrawal/#/home/
[4] http://kellybroganmd.com/stop-madness-coming-psych-meds/
[5] http://kellybroganmd.com/homicide-and-the-ssri-alibi/

Read More At: KellyBroganMD.com

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Kelly Brogan, MD

Kelly Brogan, M.D. is a Manhattan-based holistic women’s health psychiatrist, author of the New York Times bestselling book, A Mind of Your Own, and co-editor of the landmark textbook, Integrative Therapies for Depression. She completed her psychiatric training and fellowship at NYU Medical Center after graduating from Cornell University Medical College, and has a B.S. from MIT in Systems Neuroscience. View full bio. Want to share this article on your own blog? View our reposting guidelines.

Rose: Recovery from Depression after 25 Years of Psychiatric Medication

Source: Dr. Kelly Brogan M.D.
November 4, 2016

Dr. Kelly Brogan sits with one of her patients, Rose, as they discuss Rose’s journey through depression and 25 years of psychiatric medication. http://kellybroganmd.com/rose-recover…

For a review of her landmark book, A Mind Of Your Own, please read this.