Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants

Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants
Source: PreventDisease.com
Dave Mihalovic
March 28, 2017

Originally published on PreventDisease.com.

Despite no evidence of its effectiveness to prevent disease, public health agencies and the medical community insist that infants and children between the ages of 2 and 12 months require up to four shots of the Pneumococcal Conjugate Vaccine (PCV). Now new research finds a substance in turmeric, curcumin, may outperform the vaccine in providing long lasting protection against potentially deadly lung damage in infants.

Curcumin Found To Outperform Pneumococcal Vaccines In Protecting Infants

Pneumococcal bacteria are the most common cause of bacterial infections in children and a frequent cause of infections in adults. Infection starts in the nose or throat where it may persist for weeks or months. Pneumococcal infections are also the most common complication of seasonal influenza.

Researchers at Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed), using disease models, found curcumin provided long-term protection against the damage caused by inadequate lung function.

Their study, published online by the American Journal of Physiology, Lung Cellular and Molecular Physiology, found curcumin provided protection against bronchopulmonary dysplasia (BDP), a condition characterized by scarring and inflammation, and against hyperoxia, in which too much oxygen enters the body through the lungs.

Virender K. Rehan, MD, the LA BioMed lead researcher who authored the study said this was the first study to discover long-term benefits using curcumin to protect lung function in infants. “Curcumin is known to have potent antioxidant, anti-inflammatory and anti-microbial properties, making it a promising therapy,” Dr. Rehan stated.

BDP is considered to be one of the most common chronic lung diseases of infancy in the U.S. and labeled as a pneumococcal clinical risk group to be targeted with up to four doses of the Pneumococcal conjugate vaccine between the ages of 2 and 12 months. The first shot is usually given when the child is 2 months old. The booster shots are then given at 4 months, 6 months, and 12 to 15 months of age. Physicians are also recommending a child who is between the ages of 24 months and 5 years old should receive 1 or 2 additional doses of this vaccine.

Dr. Manjeet Kumar, specialist in pediatric medicine says the finding could revolutionize the pneumococcal vaccine schedules for children before the age of one year. “We know the Pneumococcal conjugate vaccines have been particularly ineffective in the last decade for most children and Dr. Rehan’s study is demonstrating a long-term protective mechanism which is now absent through standard vaccination practices,” he stated.

Pneumococcal conjugate vaccines claim to prevent diseases caused by seven of the most common types of pneumococcal bacteria, however emerging evidence is showing these claims to be exaggerated. “It appears to be protecting against serious forms of the disease less than 20% of the time, depending on the person,” stated Dr. Kumar. This is a large discrepancy from the 97% effectiveness claimed by health authorities.

Dr. Kumar emphasized the wealth of scientific literature supporting curcuminoids in disease prevention and hopes to see such treatments expanded throughout mainstream medicine. “We have hundreds of scientific studies supporting curcuminoid and curcumin derivatives in preventing disease, with enhanced biological activity and far more stable and bioavailable than current medications and vaccines on the market–it is no surprise they are outperforming pharmaceuticals.”

Curcumin derivatives are currently being synthesized by both pharmaceutical and natural health industries due to their potency and antioxidant activity. Studies suggest that the bioavailability of curcumin and possibly its derivatives is greatest in the lungs and colon protecting from a diversity of cancers.

Dr. Kumar will soon be involved in clinical trials to conduct active surveillance for invasive pneumococcal disease to assess the serotype and antibiotic resistance patterns and provide conclusive evidence on how curcumin derivatives are now outperforming all pneumococcal vaccines and medications to designated risk groups.

One of the most comprehensive summaries of a review of 700 turmeric studies to date was published by the respected ethnobotanist James A. Duke, Phd. He showed that turmeric appears to outperform many pharmaceuticals in its effects against several chronic, debilitating diseases, and does so with virtually no adverse side effects.

Alzheimer’s 
Duke found more than 50 studies on turmeric’s effects in addressing Alzheimer’s disease. The reports indicate that extracts of turmeric contain a number of natural agents that block the formation of beta-amyloid, the substance responsible for the plaques that slowly obstruct cerebral function in Alzheimer’s disease.

Arthritis 
Turmeric contains more than two dozen anti-inflammatory compounds, including sixdifferent COX-2-inhibitors (the COX-2 enzyme promotes pain, swelling and inflammation; inhibitors selectively block that enzyme). By itself, writes Duke, curcumin – the component in turmeric most often cited for its healthful effects – is a multifaceted anti-inflammatory agent, and studies of the efficacy of curcumin have demonstrated positive changes in arthritic symptoms.

Cancer 
Duke found more than 200 citations for turmeric and cancer and more than 700 for curcumin and cancer. He noted that in the handbook Phytochemicals: Mechanisms of Action, curcumin and/or turmeric were effective in animal models in prevention and/or treatment of colon cancer, mammary cancer, prostate cancer, murine hepato-carcinogenesis (liver cancer in rats), esophageal cancer, and oral cancer. Duke said that the effectiveness of the herb against these cancers compared favorably with that reported for pharmaceuticals.

Weight Loss 
Dietary curcumin can stall the spread of fat-tissue by inhibiting new blood vessel growth, called angiogenesis, which is necessary to build fat tissue. Curcumin-treated groups have been found to have less blood vessel growth in fat tissue. Blood glucose, triglyceride, fatty acid, cholesterol and liver fat levels also were lower.

Parkinson’s 
A team of researchers has now demonstrated that slow-wriggling alpha-synuclein proteins are the cause of clumping, or aggregation, which is the first step of diseases such as Parkinson’s. A new study led by Ahmad, which appears in the Journal of Biological Chemistry, shows that curcumin can help prevent clumping.

“Our research shows that curcumin can rescue proteins from aggregation, the first steps of many debilitating diseases,” said Lisa Lapidus, MSU associate professor of physics and astronomy who co-authored the paper with Ahmad. “More specifically, curcumin binds strongly to alpha-synuclein and prevents aggregation at body temperatures.”

When curcumin attaches to alpha-synuclein it not only stops clumping, but it also raises the protein’s folding or reconfiguration rate. By bumping up the speed, curcumin moves the protein out of a dangerous speed zone allowing it to avoid clumping with other proteins.

– Only 1 percent of the elderly in India develop Alzheimer’s disease – this is one-quarter the rate of Alzheimer’s development in North America. This difference is thought to be due in part to regular consumption of curry in India.
– Daily intake of curcumin may decrease the risk of developing polyps in the colon, which in turn, decreases the risk of developing colorectal cancer.
– Regular consumption of turmeric may help to ease pain and inflammation that accompanies arthritis.
– Curcumin may be helpful in the treatment of some cases of cystic fibrosis.
– Curcumin can help to effectively treat skin cancer cells.
– Turmeric may help to prevent the spread of breast cancer cells.

The medicinal properties of turmeric are so significant that the National Institutes of Health is currently conducting clinical trials to determine if turmeric (curcumin) should be a part of conventional treatment recommendations for more than a dozen different diseases.

In Ayurvedic medicine, turmeric is thought to have many medicinal properties and many in India use it as a readily available antiseptic for cuts, burns and bruises. It is also used as an antibacterial agent.

Read More at: GreenMedInfo.com
__________________________________________________________________________

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Surprising Side Effects of Tylenol

Surprising Side Effects of Tylenol
Source: GreenMedInfo.com
Dr. Kelly Brogan
March 5, 2017

Originally published on KellyBroganMD.com

You know Tylenol can relieve a headache, but are you aware it can cause other side effects, such as increased risk of death or heart toxicity?

Tylenol: Helping or Hurting?

Have you ever popped a Tylenol to push through that annoying headache and get on with your day? Most of us have. Each week, millions of Americans take one of the 600 medicines that contain acetaminophen, Tylenol’s active ingredient, for various aches and pains. Acetaminophen is the most common drug ingredient in the US, but this ‘harmless drug’ is linked to over 110,000 injuries and deaths per year.

How can Tylenol, which is doled out like candy, be bad for you? Amazingly, no one really knows how acetaminophen works [1], but people do know that this drug gets to your brain. Tylenol in your brain is concerning because it depletes glutathione [2], an antioxidant that is especially necessary for brain health. Our bodies depend on antioxidants to balance oxidative damage and inflammation. If you’re popping a Tylenol with your morning antioxidant-rich KB Smoothie, Tylenol may rob you of the smoothie’s benefits!

Beyond Liver Damage

Most people have heard that Tylenol can damage the liver (has anyone ever drunkenly warned you to take a Motrin, not a Tylenol, to prevent a hangover?). But since everything in our bodies is connected, it’s not surprising that Tylenol can do damage beyond your liver. A recent study showed that people who took Tylenol had increased risks of death, heart toxicity, gastrointestinal bleeding, and kidney damage [3]. Importantly, people who took more Tylenol suffered more damage.

It’s also scary how Tylenol affects mood. After swallowing 1000 mg of Tylenol, people exhibited less empathy and blunted positive emotions. For reference, 1000 mg is two extra-strength Tylenol tablets, and the ‘safe’ range is 3000 mg per day. This means that popping two Tylenols can affect you physically and emotionally!

If you’re pregnant or looking to become pregnant, please be especially careful about taking Tylenol. Research has shown that children exposed to acetaminophen in the womb had behavioral, communication, and motor skill problems. Another study linked prenatal acetaminophen exposure with increased ADHD-like behaviors and medication use.

What about other painkillers?

Hopefully you’re convinced to think twice before taking a Tylenol, but what about other pain-relievers like Motrin, Aleve, or Advil? These non-steroidal anti-inflammatory drugs (NSAIDs) must be safe, since thirty million people take them every day! Not so fast…

Women who recognize the importance of hormonal balance should be wary. NSAIDs can mess with ovulation, especially progesterone levels, after only 10 days of use [4]. Additionally, NSAIDs injure the small intestine; in one study, 71% of NSAID users showed small intestinal damage, compared to 10% of non-users [5]. Damaged intestines can lead to intestinal permeability, or “leaky gut.” Leaky gut has been linked to depression, ADHD, and allergies.  NSAIDs can cause leaky gut [6] and harm your microbiome, the trillions of beneficial bacteria that live in and on us. Disrupting our bacteria can do more damage than we realize!

How can I relieve my headache?!

Now that you know the surprising dangers of Tylenol and other NSAIDs, what should you take for headaches and other aches and pains? Turmeric, the yellow root found in curry powder, contains a powerful anti-inflammatory and pain reliever called curcumin. This has been used in Ayurvedic and Chinese medicine as a treatment for pain, digestive disorders, and wound healing for centuries. Many studies show the beneficial effects of curcumin; curcumin works as well as ibuprofen to alleviate pain from knee osteoarthritis [7] and PMS [8]. Next time you have a headache, try 1-2 grams of curcumin – or a turmeric latte!

 

Benefits of Turmeric Curcumin for Inflammatory Orbital Pseudotumor

Source: NutritionFacts.org
Dr. Greger
January 30, 2017

DESCRIPTION: From conjunctivitis, to uveitis, to a low-grade form of non-Hodgkin’s lymphoma, there is something in the spice turmeric with dramatic anti-inflammatory effects.

The Herbal Remedy EVERYONE Should Know About: Turmeric Golden Honey Can Fight Weight Gain, Relieve Pain & Combat Inflammation

Turmeric
Source: NaturalNews.com
Sarah Landers
August 15, 2016

You might have heard about the many health benefits of turmeric – or maybe you still think of this popular spice as only belonging in your spice rack. Either way, you may be surprised to find out that a simple combination of turmeric and honey (known as “golden honey”) is an extremely useful natural remedy, as recently reported by Natural News.

Turmeric has anti-inflammatory and anti-carcinogenic properties that make it very good for your health. It is also able to destroy bacteria that cause diseases, aiding your body’s natural defense system. Combine turmeric with honey – which has its own antibacterial properties – and you have a pretty strong natural remedy. In fact, according to Healthy and Natural World, turmeric golden honey is considered to be the strongest natural antibiotic.

How to make this remedy

Combine 3.5oz of raw organic honey with one tablespoon of turmeric powder and mix well. Store in a sealable glass container.

As soon as you exhibit the first symptoms of cold or flu, start to take the remedy in the following quantities:

  • On day one, take half a teaspoon every hour.
  • On day two, take half a teaspoon every two hours.
  • On day three, take half a teaspoon three times a day.

Turmeric and weight control

Turmeric actually melts away body fat, according to research from Tufts University in Boston. Scientists discovered that curcumin – which is the active ingredient in turmeric – reduced weight gain and total body fat in mice. Study authors explained: “By diminishing the sediment of fat, relaxing the lymphatic return, and refraining the apoptosis of beta cells, the curcumin might significantly decrease the level of insulin resistance and leptin resistance caused by the high fat diet.”

Turmeric and pain relief

According to Bel Marra Health, turmeric is actually a natural pain reliever – again thanks to its powerful active ingredient, curcumin. Its antioxidant properties help to get rid of free radicals before they can do any damage, and also combat inflammation brought on by osteoarthritis, making turmeric a natural remedy for pain.

Turmeric and inflammation

Turmeric is competitively effective when compared with a class of steroid medications known as corticosteroids which are used to manage chronic inflammation. Curcumin and resveratrol (also found in turmeric) can be helpful in the fight against tumor cells, by reducing their propensity to spread to other parts of the body, and reducing their ability to inflame local regions.

Various turmeric studies have been carried out using injectable forms of the spice – which is more bioaccessible than turmeric taken orally. According to Natural Health 365, researchers believe that curcumin has chemopreventive properties, helping it to combat cancers of the digestive tract, skin and mouth in animal studies. Curcumin not only triggers the activity of natural carcinogenic-detoxifying enzymes, but it also inhibits cancer calls from growing and spreading.

Spicy tropical smoothies

Since turmeric is one of the best natural anti-inflammatories you can consume, it is worth incorporating it into your diet on a regular basis. Check out the following amazing recipe for a spicy tropical smoothie; simply blend these ingredients together:

  • 1 cup of coconut milk
  • 1/2 cup of pineapple chunks
  • 1 banana
  • 1/2 teaspoon of turmeric
  • 1/4 teaspoon of freshly ground black pepper
  • 1 tsp of honey or maple syrup

Read More At: NaturalNews.com

Sources include:

Blogs.NaturalNews.com

NaturalHealth365.com

BelMarraHealth.com

NaturalNews.com

HealthyAndNaturalWorld.com

Science.NaturalNews.com

Striking with the Root: Turmeric Curcumin and Ulcerative Colitis

Source: NutritionFacts.org
Dr. Greger
May 30, 2016

DESCRIPTION: A double-blind, placebo-controlled trial found a dramatic effect of the anti-inflammatory spice pigment, curcumin, against inflammatory bowel disease.

Targeting Cancer Stem Cells with NonToxic Therapies

This article is copyrighted by GreenMedInfo LLC, 2016
Visit our Re-post guidelines
Targeting Cancer Stem Cells with NonToxic Therapies

Source: GreenMedInfo.com
Dr. Jeffrey Dach, MD
March 28, 2016

Originally published on JeffreyDachMD.com

When it comes to cancer treatment, chemotherapy does more harm than good.  There are other, non-toxic approaches that are worth exploring.

When Jim was 36 year old, he was diagnosed with acute myeloblastic leukemia with symptoms of fatigue, anemia, and extremely high white count on his blood panel. Over three years, Jim received seven chemotherapy treatments, each one giving him a temporary remission shorter than the last one.  Eventually the chemotherapy was no longer effective, the cancer cells became resistant to chemotherapy.  After exhausting all of the usual treatments, the doctors offered Jim allogeneic hematopoetic stem cell transplantation, a procedure which obliterates the patient’s bone marrow with high dose chemotherapy.  The patient is then “rescued” with donor bone marrow stem cells from a family member or donor bank.  This procedure is associated with considerable morbidity and mortality from infection and graft vs. host disease.   The high dose chemotherapy produces permanent, irreversible infertility.  Jim had the procedure and is alive and doing well three years later.  Image (below) poster courtesy of Cancer Stem Cell Meeting 2012 Cambridge Cancer Stem Cell Symposium.

Targeting Cancer Stem Cells with NonToxic Therapies

 

What can we learn from Jim’s story?

The first lesson is that hematologic malignancies, and all other cancers for that matter, tend to  come back (relapse) even after complete remission induced by cytotoxic chemotherapy.  For many years, the reason for this cancer recurrence was unknown.  However, in the past decade, the reason has been discovered.

 

Two Populations of Cancer Cells

There are actually two distinct populations of cancer cells in the cancer victim.  The bulky tumor masses are caused by rapidly replicating cancer cells, highly sensitive to killing effects of chemotherapy.  However, a  subset of these cancer cells lurk within the tumor mass, hiding in a dormant state, not actively replicating.  These are the cancer “stem cells” which are resistant to conventional cytotoxic chemotherapy, biding their time, waiting for a future opportunity to reactivate and seed metastatic cancer throughout the  body.

Targeting Cancer Stem Cells with NonToxic Therapies

Above image courtesy of Case Western Reserve Cancer Stem Cell Conference.

This explains Jim’s futile experience with chemotherapy which kills off the rapidly replicating leukemia cells, while leaving the dormant leukemia “stem cells” unharmed.  This is also true for most other solid organ cancers.  The solution, of course, is to address the dormant cancer “stem cell”, at the same time as the rapidly replicating cancer cells.(1,1A)

Unfortunately,  modern day oncology/ hematology doctors are oblivious to this important lesson, and continue to mindlessly treat their patients with the same chemotherapy protocols as before.  Even though this information is in their own oncology/hematology journals,  they cannot bring themselves to acknowledge it.

Sadly, since their doctors will not help them, patients are left to fend for themselves.  In order to get off the chemotherapy merri-go-round, the patient must learn about non-toxic targeted therapies which kill cancer stem cells.  These are widely available.  As we will see below, some of these therapies are supplements at the health food store, and some are common drugs  requiring a doctor’s prescription.  With knowledge of non-toxic targeted therapies,  a durable remission after the last chemotherapy treatment can be achieved.

Many Natural Substance Target Cancer Stem Cells(12)

You might be surprised to know there are 3,000 plant species having anti-cancer activity.(1B)  In fact, there are hundreds of non-toxic natural substances that target cancer stem cells. (12)  There are so many to choose from, one must be selective, so we will discuss only a few of them below: (10-19)

Curcumin

The food spice, Curcumin (tumeric) is widely available as a nutritional supplement in highly absorbance forms such as Meriva(r), Cogumen (Longvida) or Lipospheric Curcumin.

Dr Huang reports in 2016 that “Curcumin Induces Apoptosis of Colorectal Cancer Stem Cells by Coupling with CD44 Marker”.

Dr Huang studied colorectal cancer stem cells, and found curcumin couples with the CD44 cancer stem cell membrane marker,  and “might have some blocking effect on the transport of glutamine into the cells, thus decreasing the glutamine content in the CD44+ cells and inducing apoptosis.”(2)

Dr Chung reported in 2015 that both “Curcumin and EGCG Epigallocatechin Gallate Inhibit the Cancer Stem Cells . (3) Dr Chung reported the cancer stem cell marker was denoted by the CD44+ protein.  The CD44+ cell population decreased following curcumin and EGCG (from Green Tea). (3)

Dr Hasanali in 2012 reported that Curcumin inhibits Nuclear Factor Kappa Beta activation and Downregulate Cyclin D1 in Mantle Cell Lymphoma, thereby inducing apoptosis. (4) Left image: molecular structure of curcumin courtesy of Wikimedia commons.

Dr Shishodia in 2005 reported that “Curcumin inhibits constitutive NF-κB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma.” (5)

The authors reported:

“the expression of all NF-kappaB-regulated gene products were downregulated by Curcumin leading to the suppression of proliferation, cell cycle arrest at the G1/S phase of the cell cycle and induction of apoptosis as indicated by caspase activation.”

Dr Choudhuri reported in 2005 found that “Curcumin selectively induces apoptosis in cancer cells with deregulated cyclin D1 at G2 phase of cell cycle.”(6)  Normal cells were left unharmed. (6)

Drug inventors have been busy with new ideas to make curcumin more bioavailable and more effective, such as Curcumin nanodiscs. (7-9)   A massive body of basic science and medical studies on Curcumin shows the natural plant substance kills cancer stem cells while sparing normal cells as a non-toxic targeted therapy. (2-9)

Dr Peter Sordillo wrote an excellent summary of curcumin’s ability to kill cancer stem cells in ,” Curcumin and Cancer Stem Cells” AntiCancer Research 2015 (10)  Dr Sordillo reports that Curcumin inhibits release of cancer associated cytokines, IL6 and IL8, resulting in inhibition and suppression of cancer stem cells.   Both the WNT and Notch pathways are important for cancer stem cell survival.  Curcumin acts to inhibit and block multiple points along the Wnt pathway and Nctch pathways, downregulating β-catenin and the genes for VEGF, cyclin D1 and c-Myc.  Amazingly,  Curcumin has no deleterious effects on normal stem cells, and targets only the cancer stem cells.

Continue Reading At: GreenMedInfo.com

—————————————————————————-

© March 28 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here http://www.greenmedinfo.com/greenmed/newsletter.

Better Than Chemo: Turmeric Kills Cancer Not Patients

This article is copyrighted by GreenMedInfo LLC, 2016
Visit our Re-post guidelines

Better Than Chemo
Source: GreenMedInfo.com
Sayer Ji, Founder
March 1, 2016

About one hundred times less toxic than chemotherapy, turmeric extract (curcumin) was found more effective at killing colorectal cancer stem cells from patients than a popular combination of conventional drugs.

Researchers from the United Kingdom have just made a major breakthrough in cancer research by demonstrating for the first time in patient-derived colorectal cell lines that a turmeric extract (curcumin) is not only an effective adjunct agent to enhance conventional chemotherapy, but that it may be even more effective on its own.

Published this month in Cancer Letters and titled, “Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy,” the study evaluated the so-called “diet-derived agent” curcumin — the primary polyphenol in turmeric — as a possible adjunct to enhance conventional treatment of colorectal cancer with chemotherapy.

Cancer Letter curcumin

click to view the full free study

The primary role of cancer stem cells in contributing to cancer malignancy as well as resistance to conventional treatment is addressed in the study. Whereas traditional cancer research methods focus on a treatment’s ability to reduce tumor volume (or the number of cells in a cancer cell culture), the cancer stem cell theory acknowledges that treatments have highly differential effects on the different cell types that comprise the tumor; namely, whereas the relatively benign daughter cells of a tumor may die when exposed to chemotherapy, the relatively chemotherapy-resistant cancer stem cell population (so-called “mother” cells) can actually increase in number as the tumor volume decreases, resulting in creating an albeit smaller but far more dangerous, treatment-resistant tumor.

The study design and results were summarized in the abstract below:

Here, we utilised patient-derived colorectal liver metastases (CRLM) to assess whether curcumin may provide added benefit over 5-fluorouracil (5-FU) and oxaliplatin (FOLFOX) in cancer stem cell (CSC) models. Combination of curcumin with FOLFOX chemotherapy was then assessed clinically in a phase I dose escalation study. Curcumin alone and in combination significantly reduced spheroid number in CRLM CSC models, and decreased the number of cells with high aldehyde dehydrogenase activity (ALDHhigh/CD133−). Addition of curcumin to oxaliplatin/5-FU enhanced anti-proliferative and pro-apoptotic effects in a proportion of patient-derived explants, whilst reducing expression of stem cell-associated markers ALDH and CD133. The phase I dose escalation study revealed curcumin to be a safe and tolerable adjunct to FOLFOX chemotherapy in patients with CRLM (n = 12) at doses up to 2 grams daily.”


As you can see above, the researchers discovered that curcumin is both a safe and effective adjunct in the treatment of colorectal cancer. They noted the significance of these findings by pointing out that this was “the first time that curcumin may enhance oxaliplatin/5-FU-based chemotherapy in models derived directly from patients for whom the treatments are ultimately intended.” Specifically, the curcumin was able to inhibit what is known as “spheroid formation,” a 3-dimensional configuration of cells that indicates cancer stem cell driven cancer progression. Curcumin was also found to down-regulate cancer stem cell associated markers (e.g., CD44 and CD166 and ALDH activity), and various other chemical signals associated with carcinogenesis (e.g., epidermal growth factor, insulin-like growth factor and Notch). All these activities, taken together, indicate that curcumin is capable of targeting the stem cells at the heart of cancer malignancy. You can learn more about this in a previous article we wrote documenting curcumin’s ability to kill cancer stem cells: “Turmeric Extract Strikes To the Root Cause of Cancer Malignancy.” We also featured turmeric extract’s ability to selectively target cancer cells while leaving healthy ones intact in a previous article titled, “Turmeric’s ‘Smart Kill’ Properties Put Chemo & Radiation To Shame.”

Continue Reading At: GreenMedInfo.com

—————————————————————————-

—————————————————————————

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

© March 1, 2016  GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here http://www.greenmedinfo.com/greenmed/newsletter.”

7 Herbs That Block Live Cancer

Science proves these seven herbs provide powerful protection against liver cancer and liver damage of all kinds

Medicinal herbs

Source: NaturalNews.com
Ethan A. Huff
February 29, 2016

More than 10 percent of the world’s population currently suffers from some form of liver disease, whether it be fibrosis, cirrhosis, a hepatocellular carcinoma, alcoholic steatosis, or chronic hepatitis. And a great number of these folks use some kind of natural remedy as treatment rather than pharmaceuticals, according to a 2012 study published in the European Journal of Medicinal Chemistry.

Herbal remedies have gained an incredible following among liver disease sufferers, because they’re safe and highly effective, without all the harmful side effects. According to the paper, the following herbs and herb-derived remedies are among the top contenders in this natural fight against liver disease:

1) Curcumin (Curcuma long). This turmeric derivative has been used throughout Southeast Asia as a remedy for rheumatism, skin diseases, body aches, intestinal worms, diarrhea and hepatic disorders. More recently, curcumin has shown scientific benefits in treating inflammatory diseases like diabetes, heart disease, arthritis, dementia and cancer.

“Curcumin could attenuate liver injury induced by ethanol [alcohol], thioacetamide, iron overdose, cholestasis and acute, subchronic and chronic carbon tetrachloride (CCl4) intoxication,” explains the paper. “[M]oreover, it can reverse CCl4 cirrhosis to some extent.”

2) Wogonin (Scutellaria radix). This monoflavonoid compound isolated from skullcap root shows incredible promise in the treatment of both Hepatitis B and C, as well as various forms of alcoholic and non-alcoholic fatty liver disease. Unlike pharmaceuticals, wogonin doesn’t promote drug resistance, nor does it induce adverse events in patients.

“The anti-HBV activity of wogonin demonstrates its ability to suppress hepatitis B surface antigen secretion in cell culture,” the study highlights, noting that wogonin has also been shown to be effective in treating hepatocellular carcinoma cells.

3) Glycyrrhizin (Glycyrrhiza glabra). This active constituent of licorice root has long been used in the treatment of chronic hepatitis, and also possesses a host of natural anti-inflammatory and antiviral properties. Glycyrrhizin is used in traditional Chinese medicine to protect liver function and also to combat tumors.

4) Resveratrol. This polyphenolic phytochemical derived from berries, grapes and wine, has gained itself a solid reputation as one of the most potent anti-aging compounds found in nature. But resveratrol has also been shown scientifically to have hepatoprotective properties that may help protect against hepatic damage caused by free radicals and inflammatory cytokines. It also helps elevate levels of glutathione in the body and promote the formation of antioxidant enzymes, both of which help protect the liver.

Continue Reading At: NaturalNews.com

Here is How Candida May Actually Cause Cancer

candida-albicans-turmeric-735-350

Source: NaturalSociety.com
Alexandra Preston
January 15, 2016

For many years, the only known link between Candida spp. infections, and cancer was that it is an opportunistic pathogen taking advantage of the immune system damage caused by chemo. Recently, new research has found that Candida albicans can actually also promote cancer by producing carcinogens, causing inflammation, increasing the response of Th17 cells, and molecular mimicry of our own immune cells.

Candida produces the carcinogens known as nitrosamines and acetaldehyde. Nitrosamines activate specific pro-cancer genes, while acetaldehyde is a DNA-damaging carcinogen with many downstream effects. Inflammation promotes cancer by causing tissue damage and production of chemicals that promote angiogenesis, proliferation, migration, and adhesion while inhibiting apoptosis of damaged cells.

Th17 cells, which are dominant in the response to Candida infections, are also responsible for production of chemicals that can increase angiogenesis and tumor growth.

On top of this, antibodies produced against Candida albicans can mimic a receptor on white blood cells, possibly causing antibodies to be formed against our own immune cells. This is another strike against sugar and alcohol consumption in relation to cancer risk, as both alcohol metabolism and sugar fermentation lead to acetaldehyde production.

One real-life report of cancer being in association with fungal infections comes from Meinolf Karthaus, who observed three children with leukemia suddenly go into remission after antifungal treatment for “secondary” infections.

Additionally, one doctor had found fungal spores in every tissue sample of cancer that he studied, as he used saline instead of formaldehyde to transport the samples in order to preserve any possible fungi.

Natural Anti-Fungal Solutions for Candida

While pharmaceutical antifungals can cause even more damage to patients’ liver and kidneys, curcumin, the “main” medicinal compound in turmeric, may be an alternative.

On top of exhibiting potent antifungal activity against Candida, curcumin also has anticancer properties, such as the ability to destroy cancer stem cells. Curcumin has antifungal effects against other species as well. Cryptococcus, Aspergillus, Trichosporon, and Paracoccidioides strains have been shown to be vulnerable to its effects.

Additionally, curcumin can prevent resistance of Candida to the antifungal drug fluconazole. It appeared to be that resistant Candida were able to pump fluconazole out of the cell bodies. Despite curcumin’s poor water solubility and thus bioavailability, nanoparticles and fat soluble delivery methods can overcome this limitation. More traditionally, golden milk is a beverage that increases availability of turmeric to the body, and can be made at home.

Besides curcumin, clove oil may also be effective against Candida infections. In one study, even the vapour of clove essential oil was able to inhibit several species of fungi, though the oil vapor was only strong enough to temporarily stop Candida growth without killing the cells.

Continue Reading At: NaturalSociety.com